Prevent Reperfusion Injury in STEMI Management (PRISM) Working Group will involve a group of experts who will engage with cardiology community leaders to enhance our understanding of the impact a safe and effective therapeutic for IRI could have on routine clinical practice. This novel, digital collaboration platform, will facilitate peer-to-peer communications among the PRISM Working Group members. Members will have access to up-to-date data backgrounders that they can review at their convenience.